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  • Scientists melt early protein clumps and shut down Alzheimer’s damage
    Researchers found that tau proteins don’t jump straight into forming Alzheimer’s-associated fibrils—first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril growth was almost entirely suppressed. This reveals a promising new strategy: stop the precursors, stop the disease.
  • New discovery could help stop diabetes damage at its source
    Scientists identified a small molecule that interrupts a harmful protein pair linked to diabetic inflammation and tissue damage. The compound helped wounds heal faster and reduced organ stress in both Type 1 and Type 2 diabetes models. Unlike typical treatments, it works by blocking damaging signals rather than lowering sugar levels. The results point to […]
  • CRISPR brings back ancient gene that prevents gout and fatty liver
    By reactivating a long-lost gene, researchers were able to lower uric acid levels and stop damaging fat accumulation in human liver models. The breakthrough hints at a future where gout and several metabolic diseases could be prevented at the genetic level.
  • Scientists reverse kidney damage in mice, hope for humans next
    Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug candidate, the team was able to protect mitochondrial function and completely prevent kidney injury in mice.
  • New prediction breakthrough delivers results shockingly close to reality
    Researchers have created a prediction method that comes startlingly close to real-world results. It works by aiming for strong alignment with actual values rather than simply reducing mistakes. Tests on medical and health data showed it often outperforms classic approaches. The discovery could reshape how scientists make reliable forecasts.
  • Scientists find a molecule that mimics exercise and slows aging
    Exercise appears to spark a whole-body anti-aging cascade, and scientists have now mapped out how it happens—and how a simple oral compound can mimic it. By following volunteers through rest, intense workouts, and endurance training, researchers found that the kidneys act as the hidden command center, flooding the body with a metabolite called betaine that […]
  • Environmental Phenols and Growth in Infancy: The Infant Feeding and Early Development Study
    https://pubmed.ncbi.nlm.nih.gov/38753668/
  • Residential Proximity to Toxic Metal-emitting Industrial Sites and Toenail Metal Concentrations in a United States-wide Prospective Cohort
    https://pubmed.ncbi.nlm.nih.gov/38908662/
  • Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver: A Focus on Genomic Imprinting by Tissue and Sex
    https://pubmed.ncbi.nlm.nih.gov/38833407/
  • Coordinated DNA Polymerization by Polγ and the Region of LonP1 Regulated Proteolysis
    https://pubmed.ncbi.nlm.nih.gov/38932681/
  • Subchronic Inhalation Exposure to Ultrafine Particulate Matter Alters the Intestinal Microbiome in Various Mouse Models
    https://pubmed.ncbi.nlm.nih.gov/38242419/
  • Integrated Approach for Testing and Assessment for Developmental Neurotoxicity (DNT) To Prioritize Aromatic Organophosphorus Flame Retardants
    https://pubmed.ncbi.nlm.nih.gov/38922117/